Cameroon announced their World Cup squad on November 10, leaving out long-serving centre-back Michael Ngadeu-Ngadjui as coach Rigobert Song named his 26-man selection.
The coach also included two home-based players – Souaibou Marou and Jerome Ngom – who had won their first caps just hours before in a friendly against Jamaica.
The team will be captained by Vincent Aboubakar, who competed as a teenager at the 2010 World Cup and again in Brazil in 2014 when Cameroon last appeared at the finals.
It will also be a third World Cup for defender Nicolas Nkoulou, 32, and Bayern Munich attacker Eric Maxim Choupo-Moting.
Nkoulou made a comeback to the team in September after a five-year absence, having retired from the side after they won the 2017 Africa Cup of Nations.
Ngadeu was also a member of that team but had remained a regular for Cameroon since. He was omitted for the last round of friendly matches two months ago and left out again for the trip to Qatar.
Song gave no explanation for the axing of the 31-year-old Belgian-based centre back at a hastily arranged news conference where reporters were given short notice of the intention to name the squad.
Song also included teenage goalkeeper Simon Ngapandouetnbu, who is on the books of Marseille but yet to play a senior match. He is the only uncapped player in the squad.
Cameroon World Cup 2022 squad
Goalkeepers: Devis Epassy (Abha Club), Simon Ngapandouetnbu (Olympique de Marseille), Andre Onana (Inter Milan)
Defenders: Jean-Charles Castelletto (Nantes), Enzo Ebosse (Udinese), Collins Fai (Al Tai), Olivier Mbaizo (Philadelphia Union), Nicolas Nkoulou (Aris Salonika), Tolo Nouhou (Seattle Sounders), Christopher Wooh (Rennes).
Midfielders: Martin Hongla (Verona), Pierre Kunde (Olympiacos), Olivier Ntcham (Swansea City), Gael Ondoua (Hannover 96), Samuel Oum Gouet (Mechelen), Andre-Frank Zambo Anguissa (Napoli).
Forwards: Vincent Aboubakar (Al Nassr), Christian Bassogog (Shanghai Shenhua), Eric-Maxime Choupo Moting (Bayern Munich), Souaibou Marou (Coton Sport), Bryan Mbeumo (Brentford), Nicolas Moumi Ngamaleu (Young Boys), Jerome Ngom (Colombe Dja), Georges-Kevin Nkoudou (Besiktas), Jean-Pierre Nsame (Young Boys), Karl Toko Ekambi (Lyon).
Who are the star names in the squad?
Lyon forward Karl Toko Ekambi has scored 12 goals in 50 caps for his country and has a decent goalscoring record in France and previously in La Liga with Villarreal.
Other names to watch out for include captain Aboubakar, who has 88 caps and plays for Saudi Professional League club Al Nassr, Bayern Munich forward Choupo-Moting and Napoli midfielder Andre-Frank Zambo Anguissa.
Inter Milan goalkeeper Andre Onana will be hard to get past too.
What are Cameroon's fixtures?
What is Cameroon's World Cup record?
Cameroon first appeared at the World Cup in 1982 and since then have competed in six editions, failing to leave the group phase in all but one of those.
Their best result came in 1990 when they reached the quarter-finals in Italy, making them the first African country to do so. They failed to qualify in 2018.
This time around, after emerging top of a second-round group which included Ivory Coast, Cameroon beat 2019 Afcon winners Algeria in a two-legged tie.
But defeats to South Korea and Uzbekistan in recent friendlies won't inspire confidence.
Argentina | Australia | Belgium | Brazil | Cameroon | Canada | Costa Rica | Croatia | Denmark | Ecuador | England | France | Germany | Ghana | Iran | Japan | Mexico | Morocco | Netherlands | Poland | Portugal | Qatar | Saudi Arabia | Senegal | Serbia | South Korea | Spain | Switzerland | Tunisia | Uruguay | USA | Wales
Cameroon are currently a best price of 650/1 to win the World Cup.