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A look at what's happening in European football on Sunday:
Lionel Messi is set for his Paris Saint-Germain home debut against Lyon at Parc des Princes. But PSG coach Mauricio Pochettino will wait until the morning before deciding if Kylian Mbappe is fit to play. The striker twisted his ankle in the midweek draw against Club Brugge in the Champions League and is having a late fitness test.
PSG's fans are set for their first glimpse of Messi at home after his summer arrival from Barcelona. Messi came close to his first goal when he hit the crossbar against Brugge.
Lyon has won their previous three matches and coach Peter Bosz has spoken of playing for a win against PSG, who are looking for a sixth straight league victory.
Elsewhere, unbeaten Nice host struggling Monaco in the French Riviera derby and second-place Angers take on Nantes.
Manchester United and Chelsea face tough away games as they seek to stay unbeaten in the Premier League. United head to West Ham as Cristiano Ronaldo looks to score for the third straight game in his second spell at Old Trafford. Ronaldo netted twice against Newcastle last weekend and once in the Champions League midweek.
Chelsea visit London rival Tottenham, who have won their opening three games in the league before losing at Crystal Palace last weekend.
United and Chelsea both have 10 points after three wins and a draw.
The other match sees Brighton at home to Leicester.
Valencia's surprisingly strong start under coach JosÃ© BordalÃ¡s will be put to its first serious test when Real Madrid roll into Mestalla Stadium with the Spanish league lead up for grabs.
BordalÃ¡s has turned Valencia into a compact bloc led by Carlos Soler. The midfielder has three goals for his club to go with two more goals in World Cup qualifying for Spain this season.
Both sides are one point behind AtlÃ©tico Madrid at the top of the table.
Madrid will be without the injured Gareth Bale, while Eden Hazard is once again doubtful due to knee pain.
Real Sociedad host Sevilla in a clash of sides that aspire to challenge for a top-four finish.
Villarreal visit Mallorca seeking their first win of a so far disappointing season.
Real Betis host winless Espanyol.
It's a big early season test for both sides when struggling Juventus host perfect AC Milan in Serie A.
Juventus have just one point from three matches and are desperate for a first league victory in Massimiliano Allegri's return as coach. The Bianconeri gained some momentum with a 3-0 win over MalmÃ¶ in the Champions League, while Milan were beaten 3-2 at Liverpool for their first loss of the season.
Milan's 39-year-old striker, Zlatan IbrahimoviÄ, is expected to miss the match with an achilles injury.
Roma, who have also had a perfect start, visit Hellas Verona, who replaced Eusebio Di Francesco with Igor Tudor as coach after losing three straight.
Also, it's: Empoli vs. Sampdoria; Venezia vs. Spezia; and Lazio vs. Cagliari.
In each of Borussia Dortmund's and Union Berlin's previous meetings in the Bundesliga, the home team has won. Dortmund will need to improve a shaky defense to ensure the trend continues, while Union will hope to deny the home team's fearsome forwards. Erling Haaland already has nine goals in six games across all competitions.
Struggling Stuttgart host in-form Bayer Leverkusen, and Wolfsburg welcome Eintracht Frankfurt. Frankfurt coach Oliver Glasner is returning to his former club and hasn't had a good start at his new one. Frankfurt have only one point from their first four Bundesliga games. Wolfsburg are the only team with a 100% record.