On Sunday, the 42-year-old took to social media to share a snap from the Duke and Duchess of Sussex's 2018 wedding.
Mulroney added a black and white filter to the image and did not include a caption.
"Magical weekend with a handsome fella," Jessica wrote to her 413,000 followers.
The Duchess of Sussex and the Canadian stylist became friends while the show was filming in Toronto, with the pair bonding over fitness, fashion and female empowerment.
Mulroney eventually helped select the wedding dress that Markle's character, Rachel Zane, wore in the final episode of the legal drama.
Over the years, the duo spent time travelling, relaxing and supporting each other in their personal and professional endeavours.
In 2020, things took a turn for the worse when influencer Sasha Exeter called out her "very problematic behaviour and antics" within the fashion community, as well as supposedly using "textbook white privilege."
After Mulroney lost TV gigs and her reality show, she later apologized while referencing her friendship with Markle.
"As I told you privately, I have lived a very public and personal experience with my closest friend where race was front and centre," she penned on Instagram in response to Exeter’s claims. "It was deeply educational. I learned a lot from that. I promise to continue to learn and listen on how I can use my privilege to elevate and support Black voices."
Days later, a source told Us Weekly that the Duchess of Sussex wasn’t happy to be involved in Mulroney's drama, and the pair may have had a falling out.
"Meghan could not get over that Jessica brought up her relationship with Meghan when she commented about her 'closest friend' in the discourse with Sasha," the source said at the time.