Manchester City shipped five goals in a home league match for the first time in 17 years as they were shocked by Leicester City on Sunday.
Brendan Rodgers' men were in rampant form at the Etihad Stadium and were inspired by Jamie Vardy, who is proving quite the scourge of Pep Guardiola defences.
Tottenham were denied a win over Newcastle United by another late, late penalty in a Premier League match in 2020-21, while Leeds United enjoyed Yorkshire bragging rights over Sheffield United.
West Ham, meanwhile, put Wolves to the sword as manager David Moyes watched on television while in self-isolation.
Here are some of Opta's top numbers from a scintillating day of play...
Manchester City 2-5 Leicester City: Guardiola in uncharted territory
Guardiola had gone 685 games in all competitions in charge of Barcelona, Bayern Munich and Manchester City without his team conceding five goals. Over to you, Jamie Vardy.
The striker scored three times, two of them from the penalty spot, to take his tally to eight league goals against City since Guardiola took charge – the most of any player against a team managed by the Catalan – and inspire Leicester to a 5-2 win.
City had never conceded five in a game at the Etihad Stadium before and last let in that many in a home Premier League match against Arsenal in February 2003.
As for Vardy, he is the only player to convert two hat-tricks against a Guardiola team. The only other man to score even one such treble is Lionel Messi.
Tottenham 1-1 Newcastle United: Kane assists not enough
Harry Kane is fashioning a new name for himself as Tottenham's assist king.
He teed up Lucas Moura to open the scoring against Newcastle, thereby reaching five Premier League assists already for 2020-21 – that's only two short of his record for a single season in 2016-17 and as many as in his previous 54 league appearances.
In fact, only Ruel Fox for Newcastle in 1994-95 and Henrikh Mkhitaryan for Manchester United in 2017-18 have ever managed five assists in the opening three matchdays of a Premier League season.
Of course, it was Newcastle who got the real helping hand here, Eric Dier's unfortunate handball allowing Callum Wilson to equalise with a penalty after 96 minutes and 20 seconds, the latest any team has ever scored with their first shot on target in a Premier League match since at least 2006.
Sheffield United 0-1 Leeds United: Bamford loves the big time
Patrick Bamford only scored four Championship goals between February and late July last season. In the Premier League, he has three in three games. Some people just flourish on the biggest stages.
The striker is the first Leeds player ever to score in his first three top-flight games for the club and only the third person to net on the each of the first three matchdays for a promoted side in the Premier League. The others were Teemu Pukki for Norwich City last season and Michael Ricketts for Bolton Wanderers in 2001-02.
His header against Yorkshire rivals Sheffield United also saw Bamford become the first Leeds player to score in the first three matches of a top-flight campaign since Mick Jones back in 1968-69. They went on to win the title that season...
West Ham 4-0 Wolves: Bowen finds his feet
Jarrod Bowen scored twice against Wolves as West Ham romped to a mightily impressive win over Nuno Espirito Santo's Wolves, while boss Moyes was unable to attend after testing positive for coronavirus.
Bowen got his first brace in league football since December 2019, converting two impressive finishes to put the Hammers 2-0 ahead. He had only scored once in his first 22 Premier League outings.
With a relative dry spell in the past year apparently behind him, don't bet against the 23-year-old to build on this performance. Since the start of 2017-18, only Liverpool star Mohamed Salah (50) and Manchester City forward Sergio Aguero (38) have scored more league goals at home across England's top four divisions than Bowen (36).