The Lions of Teranga sealed their spot in the knockout stages thanks to a win against Cameroon, the country Guinea lead by three points.
A draw would be enough to see Syli National through into the next round, while Sadio Mane's Senegal will surely be resting players before the battles to come after the group stage.
Here’s everything you need to know about the AFCON game.
Date, kick-off time and venue
Guinea vs Senegal is scheduled for a 5pm GMT kick-off time later today on Tuesday 23 January, 2024.
The Charles Konan Banny Stadium in Yamoussoukro will host.
Where to watch Guinea vs Senegal
TV channel: The game will be broadcast on Sky Sports Main Event, Sky Sports Premier League and Sky Sports Ultra HDR. Coverage starts at 4.55pm GMT ahead of the 5pm kick-off.
Live stream: Subscribers will be able to watch on a live stream via the Sky Go app.
Live blog: Follow all the action with Standard Sport’s dedicated match blog.
Guinea vs Senegal team news
Francois Kamano is suspended for Guinea after his straight red card against Cameroon in their first game. Naby Keita could start, along with forward Serhou Guirassy.
Senegal will be expected to rotate after sealing their spot in the knockouts.
Guinea vs Senegal prediction
With Senegal likely to afford their squad players a chance to impress, a draw seems likely.
A 1-1 draw.
Head to head (h2h) history and results
Guinea wins: 16
Senegal wins: 28
Guinea vs Senegal latest odds
Guinea to win: 31/10
Senegal to win: 11/10
Odds via Betfair and subject to change.