Welsh goalkeeper Wayne Hennessey was sent off in the 86th minute for a cynical challenge before the Iranians pounced with the late goals.
Gareth Bale, in his record 110th appearance for his national team, failed to inspired Wales.
With the victory, Iran managed to recover from a humiliating loss against England in their opener. Wales, on the other hand, looked tired after their draw with the United States.
Senegal netted two goals in the 41st and 48th minutes before Qatar struck back in the 78th minute. The Lions of Teranga restored the lead, and claimed all three points, with an 84th-minute goal.
Netherlands 1 - 1 Ecuador
The Netherlands seized an early lead with a Cody Gakpo strike but Ecuador levelled the score with an Enner Valencia goal in the 49th minute.
The Dutch and Ecuadorians are co-leaders in Group A with Senegal also vying for a place in the last 16.
The Princess of Wales has been filmed smiling and looking happy while out shopping with Prince William. The couple were seen strolling through a car park on Saturday, in video published by The Sun, which said they were at Windsor Farm Shop, close to their home. Kate, 42, was wearing a hoodie and leggings and carried her own shopping, while the Prince of Wales was dressed in a blue coat, jeans, trainers and a baseball cap.
On paper, at least, it must have looked so straightforward. Vladimir Putin wanted to fix a presidential election to show the world that ordinary Russians love and admire him and support his war in Ukraine.
A TikTok video capturing a heated exchange between two buskers over a coveted performance spot at Pitt Street Mall in Sydney has gone viral. Singer Widya Tjong captured her confrontation with violinist Vasiliy Shapkin in a since-deleted TikTok live video that garnered over 2 million views. In the clip, Shapkin can be heard demanding Tjong give up the spot because he had allegedly been waiting for it.
In the last recorded moments before the 13-year-old boy's death, surveillance cameras showed him sitting on a scooter, surrounded by three classmates. The following day, police in a village in northern China's Hebei province made a sickening discovery: the boy's body, buried underneath a tarp in an abandoned vegetable greenhouse. Police in Feixiang district of Handan city identified the boy only by his last name, Wang.
While the Russian election results were condemned in the west, the reaction across Asia, Africa and Latin America shows a new global dynamic is emerging
Police are hunting a gang of kidnappers after footage emerged of a man being pulled into a van in broad daylight. CCTV footage shows a red van pulling up outside a house before three men get out and head down an alleyway. Moments later, the three are seen dragging a man into the van as he tries desperately to escape before they make off, in Bradford, West Yorkshire. Ali Rafiq, 40, whose CCTV camera caught the assailants, at 11am on March 6, said: "I was in total shock when I saw it.
Chinese military and state-run media on Sunday accused the United States of threatening global security, days after a Reuters report which found Elon Musk's SpaceX was building hundreds of spy satellites for a U.S. intelligence agency. SpaceX's Starshield unit is developing the satellite network under a classified $1.8 billion contract with the National Reconnaissance Office (NRO), Reuters reported on Friday, citing five sources familiar with the programme.
A collision involving a car and two personal mobility aids (PMAs) in Bukit Panjang has left a woman hospitalised and a driver arrested. Find out what happened.