After struggling since the World Cup and with the team now into the post-Gareth Bale era, manager Rob Page is under pressure.
Hopes of reaching a third consecutive European Championships finals are hanging by a thread and, realistically, they must win their three remaining games.
It will need to be another famous night in Cardiff if they are to do that, with today’s opponents in Croatia seasoned operators at this level.
Here’s everything you need to know about where to watch the game.
How to watch Wales vs Croatia
TV channel: The game will be broadcast on free-to-air coverage in the UK on Welsh language channel S4C.
Also, Viaplay subscribers will also be able to watch it on Viaplay 1. Coverage starts at 7.15pm ahead of a 7.45pm kick-off.
Live stream: Both S4C Online and the BBC iPlayer will offer a live stream.