Lift-off is scheduled for 11.59am local time (4.59pm BST) from the Kennedy Space Center in Florida, weather permitting.
It is the tenth launch of Starlink satellites and will take the total number in orbit close to 600. SpaceX boss Elon Musk ultimately hopes to create a 12,000-strong constellation in order to beam high-speed internet back down to Earth.
The launch was initially scheduled for 26 June but was delayed by 12 days as SpaceX said its team "needed additional time for pre-launch checkouts".
US Space Force's 45th Weather Squadron estimated a 60 per cent chance of favourable weather for the midday launch, though conditions have since deteriorated.
SpaceX has made a live stream of the launch available, and you can also follow The Independent's live blog below.
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